The Importance of Retrosynthesis in Organic Synthesis

  Author: Dr. Sarah Sattar Jabbar Summary: In the realm of organic synthesis, the journey from a conceptual target molecule to its tangible ...

 

Author: Dr. Sarah Sattar Jabbar

Summary:

In the realm of organic synthesis, the journey from a conceptual target molecule to its tangible realization is often fraught with challenges. 

In the world of organic synthesis, bringing a conceptual target molecule to life poses numerous challenges. Crafting a successful synthesis plan calls for not just creativity but also a methodical approach rooted in solid theoretical principles. At the forefront of this pursuit lies retrosynthesis, a method that provides a structured roadmap for breaking down complex molecules into more manageable components. 

A deep understanding of chemical substances, reaction mechanisms, and conditions is key to the efficacy of retrosynthesis. Armed with this knowledge, chemists can disassemble the target molecule into its basic elements, strategically severing bonds to reveal potential synthetic routes. By harnessing fundamental theoretical concepts and strategic disconnections, chemists can devise innovative solutions to even the most daunting synthetic puzzles. 

In our upcoming review article, we delve into the intricacies of retrosynthetic analysis, shedding light on its theoretical foundations and practical implications. From elucidating the guiding principles of retrosynthetic planning to exploring advanced strategies for synthesizing intricate molecules, our article serves as a comprehensive resource for chemists of all levels. 

Through a systematic exploration of retrosynthesis, we aim to demystify this indispensable tool and equip researchers with the confidence and precision needed to tackle synthetic challenges head-on. By illuminating the path from target molecule to synthesis plan, we aspire to inspire new discoveries and advancements in the dynamic field of organic chemistry. 

Author's Biography: 

Dr Sarah Sattar is a lecturer at the Department of Pharmaceutical Chemistry, College of Pharmacy, University of Baghdad/Iraq, specializing in organic synthesis and chemical methodology. With a passion for unraveling the intricacies of molecular design, I dedicated to advancing the frontiers of synthetic chemistry. Sarah Sattar holds a PhD. Degree in Pharmaceutical Chemistry from University of Baghdad/Iraq.

Article link: https://journalspress.com/LJRS_Volume24/The-Importance-of-Retrosynthesisin-Organic-Synthesis.pdf